| Clinic/Department | Elevator | Floor |
| Admission | | 1 |
| Ambulatory | A | 2 |
| APAC Pain Clinic | A | 4 |
| Avery Clinic | A | 4 |
| Auditorium | A | Ground Floor |
| Audiology Center | E | 3 |
| Cafeteria and Vending Machines | B | Ground Floor |
| Cardiac Cath Lab | B | 2 |
| Cardiac Diagnostic Center (EEG Services) | A | 8 |
| Cardiac Rehabilitation | C | 6 |
| Cashier | A | 1 |
| Chicago Center for Orthopedics | A | 3 |
| Chicago Spine Center | A | 3 |
| Chicago Vascular Institute (& Vein Clinic) | C | 7 |
| CIMPAR | A | 3 |
| Emergency Department | | 1 |
| Eye Surgery Center | B | 4 (Rear Doors) |
| GI Lab | B | 5 |
| Human Resources | B | 1 |
| INPATIENT FLOORS | | |
| Cardiology (Rooms 601 - 640) | B | 6 |
| Eight South (Rooms 801 - 827) | B | 8 |
| Five Northwest (Rooms 550 - 588) | C | 5 |
| Geriatric Psych | B | 7 |
| Intensive Care Unit | A | 2 |
| Joint University (Rooms 430 - 456) | B | 4 |
| Rehabilitation (Rooms 459 - 480) | C | 4 |
| Three South (Rooms 305 - 347) | B | 3 |
| Lab and Bloodwork | A | 7 |
Vanguard Medical Group | E | 3 |
| Strauss Cancer Center | E | 3 |
| Lakeshore Medical Center Lobby | E | 1 |
| Leland Lobby | C | 1 |
| Main Lobby | | 1 |
| Medical Education | C | 7 |
| Medical Records | A | Ground Floor |
| Neurology | A | 5 |
| Nuclear Medicine | A | 7 |
| Outpatient Rehabilitation | | 1 |
| Pharmacy (Hospital) | A | Ground Floor |
| Pharmacy (Walgreens) | | 1 |
| Podiatry (Foot Care Clinic) | A | 4 |
| Prayer Room | A | 2 |
| Radiation Oncology | C | Lower Level |
| Radiology | | 1 |
| Registration & Admitting | A | 1 |
| Respiratory Care and Pulmonary Lab | A | 3 |
| Seasons Hospice | C | 3 |
| Senior & Community Center | C | 1 |
| University of Chicago Bone & Joint Replacement Center | C | 8 |
| University of Chicago Gastrointestinal Disease Center | B | 5 |
| University of Chicago Ophthalmology Center | C | 8 |
| University of Chicago Plastic Surgery Center | B | 5 |
| University of Chicago Spine Center | A | 3 |
| Urology | B | 5 |
| Women's Health | C | 6 |
| Wound Healing Center | C | 7 |