The purpose of screening is early diagnosis and treatment. Screening tests are usually done for people without any current symptoms, but who may be at high risk for certain diseases or conditions.
There are several tests that doctors may use to screen for
Alzheimer's disease. Examples include:
- Neurological exam—to test the nervous system (brain, spinal cord, nerves, and muscles) for evidence of other neurological disorders
Wechsler's Logical Memory and Visual Reproduction and Kendrick Object Learning Test—may be used if you have
- Seven-Minute Screen
- Mini-Mental State Exam
- Montreal Cognitive Assessment (MoCA)
- Memory Impairment Screening
- Self-assessment cognitive test—this is a test that you take on your own to assess your memory
Genetic testing is available, but it is not routinely used in most patients. It may be done in patients with a family history of early-onset Alzheimer's. Researchers are also studying whether specialized imaging tests would be helpful in screening for Alzheimer's disease. Cerebrospinal fluid (CSF) evaluation via a lumbar puncture may play a role in the diagnosis of Alzheimer’s disease.
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Hampel H, et al. Biomarker’s for Alzheimer’s disease: academic, industry and regulatory perspectives.
Nat Rev Drug Discov. 2010;9(7):560-74.
Roalf DR, Moberg PJ, Xie SX, et al. Comparative accuracies of two common screening instruments for classification of Alzheimer’s disease , mild cognitive impairment, and healthy aging. Alzheimers Dement. 2012; Dec 20. [Epub ahead of print]
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7/6/2009 DynaMed's Systematic Literature Surveillance
https://dynamed.ebscohost.com/about/about-us: Brown J, Pengas G, Dawson K, Brown LA, Clatworthy P. Self administered cognitive screening test (TYM) for detection of Alzheimer's disease: cross sectional study. BMJ. 2009;338:b2030.
Last reviewed September 2013 by Rimas Lukas, MD
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