Diagnosis of Metabolic Syndrome
Initially, your doctor will ask about your symptoms and medical history. A physical exam will be done.
The National Cholesterol Education Program offers these criteria for diagnosing
metabolic syndrome. With this criteria, you have metabolic syndrome if you have three out of the five conditions.
occurs when extra fat tissue is found in the waist area. This has been found to have greater metabolic consequences. Central obesity may be defined as:
- In men—waist measurement greater than or equal to 40 inches (102 cm)
- In women—waist measurement greater than or equal to 35 inches (89 cm)
When your body cannot appropriately control the levels of sugar in the blood, impaired fasting glucose eventually occurs. This is defined as a fasting glucose level greater than or equal to 100 mg/dL (5.6 mmol/L). People previously diagnosed with type 2 diabetes meet this criteria.
Elevated blood pressure
is defined as a blood pressure greater than or equal to 130/85 mm Hg.
Triglycerides are a kind of fat found in your blood. This is defined as fasting blood triglycerides greater than or equal to 150 mg/dL (1.6 mmol/L).
HDL stands for high-density lipoprotein. This breaks down and removes cholesterol from the body. It is sometimes referred to as the good cholesterol. This is defined as:
- In men—HDL levels less than 40 mg/dL (1.0 mmol/L)
- In women—HDL levels less than 50 mg/dL (1.3 mmol/L)
There are a number of tests that your doctor may do. Examples include:
- Waist circumference—a measure around your hips and belly button
- Blood pressure
Your doctor will ask you to fast (not eat) after dinner the night before the test. The next morning, he will take a blood sample from your arm to test it for glucose levels.
These tests are also called lipid profile tests. Your doctor will take a sample of your blood and check your:
- Total cholesterol
- Serum triglyceride levels
- LDL cholesterol levels—LDL stands for low-density lipoprotein and is the bad cholesterol.
- HDL cholesterol levels test
Deen D. Metabolic Syndrome: time for action.
Am Fam Physician. 2004;69:2875-2882.
Gami AS, Witt BJ, Howard DE, et al. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies.
J Am Coll Cardiol. 2007;49:403-414.
Grundy SM. Metabolic syndrome: a multiplex cardiovascular risk factor.
J Clin Endocrinol Metab. 2007;92:399-404.
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome.
Reaven GM. The metabolic syndrome: requiescat in pace.
Clin Chem. 2005;51: 931-938.
Tan CE, Ma S, Wai D, et al. Can we apply the National Cholesterol Education program Adult Treatment Panel Definition of the metabolic syndrome to Asians?
Diabetes Care. 2004;27:1182-1186.
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III): Executive Summary. National Heart, Lung & Blood Institute, National Institutes of Health website. Available at:
http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3xsum.pdf. Accessed May 10, 2013.
Last reviewed May 2014 by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © EBSCO Publishing. All rights reserved.